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About Razani Lab
The Razani laboratory focuses on understanding the mechanisms of common metabolic diseases ATHEROSCLEROSIS
OBESITY
DIABETES
FATTY LIVER DISEASE
We have a particular interest in the following:
Atherosclerotic macrophages
Macrophage polarization
Foam cell formation
Adipose tissue metabolism
Adipose tissue macrophages
Liver metabolism
The autophagy-lysosome system
Lysosomal biogenesis
Lysosomal acidification
Lysosomal acid lipase and lysosomal lipolysis
Selective autophagy (particularly p62/SQSTM1)
Lipophagy
Aggrephagy
Mitophagy
mTOR signaling
Differing roles of mTORC1 and mTORC2
Nanoparticle delivery systems
iPSC (induced pluripotent stem cells)
Razani Lab News
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Trent Evans (graduate student) awarded prestigious NIH NRSA F31 grant in 2016
Lab Mascot: THE OUROBOROS
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Represents cyclicality and renewal which are the essence of the autophagy-lysosome system
(designed by Dr. Ismail Sergin - postdoctoral fellow)
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Ismail Sergin (postdoctoral fellow) chosen for oral presentation at 2016 ATVB meeting
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Astrid Rodriguez-Velez (summer undergraduate student) wins Outstanding Poster Presentation at 2016 ABRCMS conference
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Xiangyu Zhang (postdoctoral fellow) wins best poster award at the 2016 Washington University Cardiovascular Research Symposium
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Trent Evans (graduate student) selected as 2016 David and Deborah Winston Fellowship in Diabetic Cardiovascular Disease
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Se-jin Jeong has started in 2017 as our newest Postdoctoral fellow. Her expertise is in autophagy (particularly lipophagy) and atherosclerosis.
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Trent Evans (graduate student) selected for 2017 ATVB Travel Award
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