Zhang X, et al. Loss of Macrophage mTORC2 Drives Atherosclerosis via FoxO1 and IL-1β Signaling.
Jha V et al. A Critical Role for ERO1α in Arterial Thrombosis and Ischemic Stroke.
Yeh YS, et al. Subcutaneous Transplantation of White Adipose Tissue.
Ozcan M et al. Sustained alternate-day fasting potentiates doxorubicin cardiotoxicity.
Zhang X, et al. Use of acidic nanoparticles to rescue macrophage lysosomal dysfunction in atherosclerosis.
Taghrir MH, et al. Inequity and disparities mar existing global research evidence on Long COVID.
Park AC, et al. PCSK9 Pleiotropism: In the Same Vein as Statins.
Zhang X et al. Evaluation of mTORC1 signaling in mouse atherosclerotic macrophages by flow cytometry and immunofluorescence.
Arentoft A et al. HIV Antiretroviral Medication Neuropenetrance and Neurocognitive Outcomes in HIV+ Adults: A Review of the Literature Examining the Central Nervous System Penetration Effectiveness Score.
Francis GA and Razani B. Autophagy in Atherosclerosis: Not All Foam Cells Are Created Equal.
Rusu I et al. Microbial signals, MyD88, and lymphotoxin drive TNF-independent intestinal epithelial tissue damage.
Theofani E et al. TFEB signaling attenuates NLRP3-driven inflammatory responses in severe asthma.
Li J et al. Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation.
Hosseinnezhad M et al. Green miles in dyeing technology: metal-rich pumpkin extracts in aid of natural dyes.
Razani B et al. A comparative study of pathogen inactivation technologies in human platelet lysate and its optimal efficiency in human placenta-derived stem cells culture.
Akbarialiabad H, et al. Long COVID, a comprehensive systematic scoping review.
Razani B, et al. Preserving immune homeostasis with A20.
Dean JM, et al. MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression.
Stitham J, et al. Inflammasomes: a preclinical assessment of targeting in atherosclerosis.
Li Y, et al. TFEB is a master regulator of tumor-associated macrophages in breast cancer.
He A, et al. Acetyl-CoA Derived from Hepatic Peroxisomal β-Oxidation Inhibits Autophagy and Promotes Steatosis via mTORC1 Activation.
Zhang X, et al. High-protein diets increase cardiovascular risk by activating macrophage mTOR to suppress mitophagy.
Galle-Treger L, et al. Autophagy is critical for group 2 innate lymphoid cell metabolic homeostasis and effector function.
Razani B, et al. Non-catalytic ubiquitin binding by A20 prevents psoriatic arthritis-like disease and inflammation.
Evans TD, et al. TFEB drives PGC-1α expression in adipocytes to protect against diet-induced metabolic dysfunction.
Javaheri A, et al. TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy.
Evans TD, et al. Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease.
Jeong SJ, et al. p62/ SQSTM1 and Selective Autophagy in Cardiometabolic Diseases.
Park H, et al. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.
McGill JB, et al. Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.
Kalugotla G, et al. Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages.
Primeau T, et al. Assessment of Copper Nanoclusters for Accurate in Vivo Tumor Imaging and Potential for Translation.
Dick SA, et al. Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction.
Weber KJ, et al. PPARγ Deficiency Suppresses the Release of IL-1β and IL-1α in Macrophages via a Type 1 IFN-Dependent Mechanism.
Zhang Y et al. TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose.
Zhang X, et al. Classical and alternative roles for autophagy in lipid metabolism.
Evans TD, et al. TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis.
Clemente-Casares X, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis.
Zhang H, et al. CRISPR/Cas9-Mediated Gene Editing in Human iPSC-Derived Macrophage Reveals Lysosomal Acid Lipase Function in Human Macrophages-Brief Report.
Liu H, et al. Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway.
Mildenberger J, et al. N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2.
Fang L, et al. Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment.
Sergin I, et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.
Block RC and Razani B. Linking lysosomal acid lipase insufficiency to the development of cryptogenic cirrhosis.
Lee Y, et al. Keap1/Cullin3 modulates p62/SQSTM1 activity via UBA domain ubiquitination.
Evans TD, et al. Target acquired: Selective autophagy in cardiometabolic disease.
Lanza GM, et al. Anti-angiogenic nanotherapy inhibits airway remodeling and hyper-responsiveness of dust mite triggered asthma in the Brown Norway rat.
Evans TD, et al. Modulating oxysterol sensing to control macrophage apoptosis and atherosclerosis.
Block RC and Razani B. Options to consider when treating lysosomal acid lipase deficiency.
Leng S, et al. Ursolic acid enhances macropahge autophagy and attenuates atherogenesis.
Sergin I, et al. Inclusion bodies enriched for p62 and polyubiquitinated proteins in macrophages protect against atherosclerosis
Sergin I, et al. Degradation and beyond: the macrophage lysosome as a nexus for nutrient sensing and processing in atherosclerosis
Razani B and Raines EW. Can the DNA damage response be harnessed to modulate atherosclerotic plaque phenotype?
Sergin I, et al. Hypoxia in plaque macrophages: a new danger signal for interleukin-1b activation?
Emanuel R*, Sergin I*, et al. Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelae.
Sergin I, et al. Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis.
Epelman S, et al. Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.
Lodhi I, et al. Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARg activation to decrease diet-induced obesity.
Lei Y, et al. The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.
Razani B, et al. Autophagy links inflammasomes to atherosclerotic progression